That's exactly right EvilWizardCharacter, and that's just some of the ways custom 'dice' can be used to assist in gaming. Certainly you can write down skull = x effect, white shield = y effect, black shield = x effect and get a similar result. But you can use custom die to personalize your games. The end-game is that custom dice don't do anything special that a normal dice and some notes can't do - they can just look better and a bit more the part. You could put little images of rooms on them to determine where a player might be teleported, you could choose from a selection of spells a sorcerer might cast, or tactics a group of mercenaries might take to apprehend the Heroes. A trader might have 3 certain items at any given time sh/es encountered in the wild, or you might roll for different effects from the mushroom soup the Elf just had the balls to try in an alchemists laboratory. You might have a particular theme in your HQ games, whether space (spacecrusade), fantasy or I don't know, vampiric and want your dice to look respectively like a glowing energy cube, a treasure chest or a ornate jewel box.
These are just ideas, yknow?
"We use random events in our Quests to keep an element of uncertainty and suspense, but randomly generated rooms in a couple places could have the same effect. That could even be a gimmick for a whole string of Quests--perhaps questing in the mutli-tiered castle of some mad sorcerer whose random lair mirrors his random moods." - love it!